Usage of Volume Distribution

General Usage

The Volume Distribution values can be used to have an insight for certain things like:

pH

pH values of drugs depends on many factors. We can predict the pH nature of drug, in a gross level, by looking at the values of volume distribution.

• High

  A higher pH value i.e. basic nature is indicated by a higher value of Volume Distribution.

• Low

  A lower pH value i.e. acidic nature is indicated by a lower value of Volume Distribution.

Lipophilicity

The lipophilicity or lipophobicity of a drug can be grossly predicted by having a look at values of volume distribution.

• Lipophilic

  A higher value of volume distribution indicates lipophilicity of the drug.

• Lipophobic

  A lower value of volume distribution indicates lipophobicity of the drug.

How To Use This program

1. Curve

   For a certain element, if plasma concentraion in various times can be provided, the from the Conc vs time curve, one can find the best fit compartmental model from the drug.

2. Value

   Volume distribution value can be compared with some known drugs in order to have a greater insight.